Anthelmintic Activity Of Punica Granatum Ethanol Extract Against Paramphistomes In Infected Sheep

Transcript

Parasitic diseases remain a major threat to livestock production around the world, particularly in India. Paramphistomosis caused by paramphistomes are one of the most common and economically important diseases of livestock. The high incidence of resistance to chemotherapeutics, toxicity and side effects has urged the necessity of finding alternative plant-based anthelmintics against helminth parasites. Therefore, the present investigation was aimed to assess the anthelmintic effect of the rind of Punica granatum Ethanol Extract (PgEE) against paramphistomes in infected sheep. Infected sheep were treated orally with 30 and 50 mg/ml concentrations of PgEE. Eggs Per Gram (EPG) count on faeces, haematological and biochemical parameters of sheep were investigated. In PgEE-treated sheep, the egg count reduced significantly in the faeces and the reduction was proportional to dosage and duration after treatment. The maximum reduction (97.95 %) was observed on day 21 post-treatment with 50 mg/ml concentration of PgEE. In infected sheep, the haemoglobin and protein content were below standard physiological values. Improvement of haematobiochemical profile was observed in sheep after treatment with PgEE. Article Citation: Lalhmingchhuanmawii K, Veerakumari L and Raman M. Anthelmintic activity of Punica granatum ethanol extract against paramphistomes in infected sheep. Journal of Research in Animal Sciences (2014) 2(1): 079-086. Full Text: http://janimalsciences.com/documents/AS0025.pdf