In Vitro Study Of Anti-thrombotic Activity Of Lato (caulerpa Lentillifera)
This study aimed to determine the Activated Partial Thromboplastin Time (APTT) and Prothrombin Time (PT) before and after administration of Caulerpa lentillifera extract (50%, 75%, 100% concentrations), positive control, and negative control. PT and APTT were prolonged after treatment of different concentrations of Caulerpa lentillifera extracts (50%, 75%, and 100%). In APTT test, there is a significant difference between positive control and 50% and 100% Lato extract; however 75% Lato extract is comparable with the positive control. While in PT test, all concentration differ significantly with the positive control (Aspirin). Caulerpa lentillifera extract is considered a potent antithrombotic agent based on prolonged PT and APTT. A similar study may beconducted using in vivo assay instead of in vitro. Additionally, more trials and replicates can be used in the study.
-
Rating
-
Date
December 2017 -
Size
5.8MB -
Views
6,061 -
Categories