Transcript
Pharmaceutical Technology ebook series Pharmaceutical Solid Dosage and Excipient 2014 EDITORIAL Editorial Director Rita Peters
[email protected] Managing Editor Susan Haigney
[email protected] Scientific Editor Adeline Siew, PhD
[email protected] Manufacturing Editor Jennifer Markarian
[email protected] Community Editor Melanie Sena
[email protected] Art Director Dan Ward Contributing Editors Jill Wechsler
[email protected]; Jim Miller info@ pharmsource.com; Hallie Forcinio
[email protected]; Susan J. Schniepp
[email protected]; Eric Langer
[email protected]; and Cynthia A. Challener, PhD
[email protected] Correspondents Hellen Berger (Latin/South America,
[email protected]), Sean Milmo (Europe,
[email protected]), and Jane Wan (Asia,
[email protected]) 485 Route One South, Building F, Second Floor, Iselin, NJ 08830, USA Tel. 732.596.0276, Fax 732.647.1235, PharmTech.com 4 Controlled-Release Technologies Create Opportunities for Solid-Dosage Drug Formulators by Cynthia A. Challener 16 Selection of Excipients in Generic Formulations by Aloka Srinivasan 24 A Practical Guide to Hot-Melt Extrusion Scale-Up for Pharmaceutical Applications by Justin R. Hughey 30 Safety by Design—Mitigating the Risk of Medication Errors Through Product Design An Interview with Kamlesh Oza and Perry Cozzone of Colorcon 36 Using Modular Systems in Solid-Dosage Manufacturing by Pär Almhem, Reiner Lemperle, and Camilla Sivertsson 44 Obtaining User-Defined Particle Size Distribution Using Dry Granulation by Dejan Djuric 48 A Quality-by-Design Approach to Optimize In-Process Curing of EUDRAGIT NM 30 D by Thomas Dassinger, Jessica Müller-Albers, and Sascha Jautze
