Synthesis And Characterization Of Silver (core)/layered Double Hydroxide (shell) Nanoparticles

Transcript

The development of metallic Silver (Ag) core and layered double hydroxide (LDH) shell nanoparticles (NPs) holds promise in nanomedicine. This drug delivery platform may induce simultaneous therapeutic actions, i.e., hyperthermia due to plasmon resonance of Ag and apoptosis due chemotherapeutic agent within LDH, as well as provide molecular imaging capability. Herein, for the first time, Ag (core)/(Mg2+, Al3+)-LDH (shell) NPs are synthesized, and the results of characterization of the morphology, composition and surface plasmon resonance (SPR) of the core/shell NPs with varying shell thickness are reported. For the pure 45 nm Ag NP core, the wavelength for transverse SPR absorption was 395 nm, which red-shifted up to 430 nm at a LDH shell thickness of 15 nm. Additionally, the synthesis and characterization of the Ag nanorods are also presented. The observation of longitudinal SPR absorption in the near infrared range makes Ag nanorods a more appropriate core material.